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Effect of mTORC Inhibition on Neuron-Glioma Progression

Columbia University

Eligibility

Undergraduate Only

Accepts Applications Until

Dec 20, 2025

Project Duration

Flexible

Description

We are a young vibrant lab looking for undergraduate students to join Dr. Brian Gills research team. Our lab's interest is in brain tumor-neuron interactions and how they contribute to tumor associated epilepsy and tumor progression. We are investigating if mTORC inhibition can reduce tumor associated seizures and reduce neuron-driven tumor progression. We use a variety of novel techniques to investigate these goals including ex vivo patch clamp recordings of mouse glioma models; ex vivo human tissue microelectrode recordings; and in vivo calcium imaging of peritumoral excitatory neurons in mouse glioma models. Projects are available for students interested in computational analysis.

Required Skills

MATLAB, Python, R programming experience preferred.

Additional Information

Lab/Building Location (if available): Irving Cancer Research Centre (1130 Saint Nicholas Avenue 168th St)

Please include a brief description of your research goals.

Compensation

Other

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