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Immunoengineering RNA and Protein Therapeutics

Columbia University

Eligibility

Undergraduate Only

Accepts Applications Until

Dec 20, 2025

Project Duration

Flexible

Description

Harnessing the power of the endogenous immune system has emerged as a powerful strategy for disease prevention and treatment, spanning traditional vaccines to modern cancer immunotherapies. The Yousefpour Lab focuses on developing next-generation RNA- and protein-based vaccines and immunotherapies by integrating synthetic biology, protein engineering, and biomaterial science.

We have multiple positions available. Students will contribute to the design and development of RNA-and protein-based vaccines, including optimizing RNA sequences, studying immune response mechanisms, and exploring innovative vaccine formulations. The projects will also involve broader work on RNA-based therapeutics, such as engineering synthetic biology platforms and biomolecular drug delivery strategies. Through these projects, students will gain hands-on experience in molecular biology techniques, in vitro cell culture, and characterization assays. Those who commit to a longer-term involvement will be encouraged to pursue an independent aspect of the project. If desired, students can also receive mentorship on post-graduate plans. Students are also expected to contribute to general lab maintenance and help with shared lab responsibilities as needed.

Required Skills

No prerequisites are required. However, students should be eager to learn, ask questions, and be highly motivated. Ideal candidates are open to a longer-term commitment. Students are also expected to contribute to general lab maintenance and help with shared lab responsibilities as needed.

Additional Information

Lab/Building Location (if available): Lasker 516

Positions are considered for Spring 2026

Compensation

Other

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